This paper presents the findings of an investigation on the compressive strength of Cocoa Pod Husk Ash (CPHA) concrete and its resistance to tannery waste aggression, as well as the compressive strength regression model. The CPHA used was obtained by controlled burning of cocoa pod husk in an incinerator to a temperature of 600-630oC, and after allowing cooling, ground and sieved through sieve 425 μm and characterized. The compressive strength of CPHA-Concrete was investigated at CPHA additions of 0, 0.2, 0.4, 0.6, 0.8 and 1.0 %, respectively by weight of cement. A total of seventy two 150 mm cubes of CPHA-Concrete of 1: 2: 4 mix and water-cement ratio of 0.55 were tested for compressive strength at 3, 7, 28 and 56 days of curing. Eighteen 150 mm cubes were initially cured in clean water for 28 days before exposure to attack from tannery waste solution for 28 days and tested in compression. The concrete compressive strength was also modeled using Minitab statistical software to establish regression model. The results of the investigations showed that Cocoa Pod Husk Ash (CPHA) is predominantly of K2O (88.26%) and MgO (3.59%) and addition of up to 0.6% CPHA increased the compressive strength and resistance of concrete exposed to acidic environment. The regression model of CPHA-Concrete compressive strength was developed with R2 value of 0.793 and was adequate for prediction of concrete compressive strength.
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